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Senior Scientist - Technology

Functional Area: Chemistry
Salary Range: Up to £45k per annum
Location: Cambridge UK
Reports to: Principal Scientist
Job Type: Full Time / Permanent

Company Overview

Sphere Fluidics is an established Life Science company which provides instruments and specialist consumables for the global pharmaceutical and academic research community. The company has recently raised £26M in investment. We are growing quickly and have impressive plans requiring new and exciting skill-sets and global capabilities to support this period of growth.

The Role

The R&D department is now looking to recruit a Senior Scientist to join R&D team working on the research and development of novel materials, new workflows and cell detection/sensing approaches for cell-based applications. The successful candidate will work in a multi-disciplinary team on a range of exciting and leading-edge projects.

Main Duties and Responsibilities

  • Work in a small team.
  • Contribute expert knowledge and skills in areas pertinent to microdroplet technology and applications.
  • Develop and implement novel materials and reagents, derivatives of various forms of microdroplets, and new workflows into Sphere picodroplet microfluidic systems and products.
  • Effective liaison across all R&D teams, as well as the Company Commercial and Operation departments.
  • Manage and support agreed projects aligned to meet the Company’s R&D strategy and needs.
  • Develop technical specifications for new products.

Knowledge, Skills & Experience

  • PhD in materials science, nanotechnology, engineering, biochemistry, cell biology, immunobiology, or other related fields with minimum 3 years of post-PhD track record of research or industrial experience.
  • Strong background in physics, mechanical engineering, mass spectrometry, impedance spectroscopy is advantageous.

Proven experience in two or more of the following areas is essential:

  • Microfluidics, acousto-fluidics or opto-fluidics, micro-magnetofluidics.
  • Mass spectroscopy, impedance, image analysis, cyclic voltammetry, NMR spectroscopy, fluorescence spectroscopy related to biomolecule detection and screening.
  • Lipid chemistry and application including synthesis of lipid vesicles/nanoparticles, functionalization with biomolecules, drug encapsulation and screening etc.
  • Real-time microdroplet imaging and high throughput processing and analysis using microscopy.
  • On-chip cell imaging and manipulation techniques including acousto-force microscopy, micro-rheology, magneto-twisting cytometry, nano/micro particle tracking, micro-plate stretching etc.
  • Miniaturized electrode design on flexible substrates by printing or other techniques.
  • Knowledge in cell-based assay techniques (spheroid/organoid on a chip, microbead-based tissue scaffolds, drug testing etc) is desirable.
  • Knowledge of medicinal chemistry and related compounds including silicone oils, herbal extracts and their application to cell therapies.
  • Experience in microdroplet generation, double emulsion, fluid dynamics is desirable but not essential.

Personal Attributes

  • Proven leadership skills.
  • Exceptional critical thinking and problem-solving skills are essential.
  • Effective communication and presentation skills are essential.
  • Ability to work and deliver tasks within a set timeline is essential.
  • Ability to work both independently and collaboratively is essential.

The successful candidate will work in a multi-disciplinary team and should be enthusiastic, collaborative and exhibit excellent communication skills.

The Benefits

  • 25 days holiday plus bank holidays.
  • Employee Share Options (EMI Scheme).
  • Company pension scheme with Aviva (employer contributes 8%).
  • 4x Life Insurance & Critical Illness Cover.
  • Private Medical Insurance with Vitality.
  • Health Cash Plan.
  • Group Income Protection.
  • Employee Assistance Program.
  • Cycle to Work scheme.
  • Learning & Development opportunities for career growth.
  • Long Service bonus – up to 5 extra days holiday.
  • Recruitment referral scheme (£1,000).
  • Flexible working hours to support work-life balance.

Sphere Fluidics strives to be an equal opportunities employer. Our policy is to recruit a diverse workforce and follow the guidelines of the Equality Act.


We’d love to hear from you. To apply for this role, please e-mail your CV to: