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Cyto-Mine® Chroma:
Unmatched Single-Cell Analysis with Multiplexing Power

Automate. Accelerate. Analyze millions of cells in a single day.

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What is Cyto-Mine® Chroma

Cyto-Mine® Chroma is a multiplexing-capable, fully-automated single cell analysis platform that can encapsulate, analyze, sort, and dispense viable single cells.

Leveraging picodroplet technology, single cells are encapsulated in tiny volumes of liquid (e.g. cell culture media). Cyto-Mine® Chroma automates incubation of the cells and cellular output, proliferation, and/or interactions can be measured using standard fluor-based assays.

The automated system screens millions to tens of millions of viable single cells and simple controls allow users to select and dispense targeted desired cells for downstream outgrowth.

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Save time
Functionally analyze millions to tens of millions of single viable cells in a single day shortening standard workflows by months
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Enhanced detection
Able to detect secreted cellular products
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Easy to use
Simple-to-use workflows eliminate the need for extensive training on overly complex systems
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Flexible
Multiple assays provide flexibility in use cases and integration in your research pipeline
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Automated
Automate tasks that require manual labor and handoff between multiple pieces of equipment

Workflow Example

Ultra high-throughput screening of viable single cells in picodroplets

Cyto-Mine Chroma workflow

Cyto-Mine® Chroma Capabilities

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Multiplexing capabilities

Enables multiple readouts within a single experiment optimizing target cell selection 

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Picodroplet technology

Enables analysis of millions to tens of millions of single viable cells per experiment 

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Pre-loaded workflows and integrated control software

Ensures ease of use

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Fluor-based readouts

Allows flexibility in experimental design

View our latest poster presentation featuring Cyto-Mine® Chroma

Highlights include:

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Faster project completion
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Multiplexing capabilities
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Rapid identification and isolation of rare cells
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Assurance of monoclonality in selected cells
View here
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Specs

Cyto-Mine® Chroma Specifications

Cell Analysis Throughput

2 Million cells per experiment (40 Million Pooled cells or 80,000 Single cells)

Chemistry

Picodroplet encapsulation

Fluorescent Capabilities

(Excitation / Detection)
Up to 4 colors

Cell Viability

Viable cell analysis and dispensing for outgrowth

Consumables

Cyto-Mine® Cartridges, Cyto-Surf® Reagents

Software

On-board control, analysis, and data management software

Applications

Cell Line Development, Antibody Discovery, Cell Therapy
Cyto-Cartridge®

Discover the Cyto-Cartridge®

The Cyto-Cartridge® is the core of the Cyto-Mine® platform, providing all the necessary microfluidics for implementing picodroplet workflows.

The disposable cartridge is designed to be easy-to-use, ensuring zero cross-contamination between runs and maintaining the integrity and quality of your cells for each experiment.

Cyto-Cartridges® are manufactured from fully biocompatible materials under our ISO 9001 quality management system, in a clean environment.

View Interactive Cyto-Mine® Brochure
Cyto-Cartridge animation
Applications

How to think big

Picodroplets have numerous applications in life science R&D. Here are some examples to fire up your imagination.

Antibody Discovery
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Antibody Discovery

Antibody Discovery

Are you struggling to screen your repertoire of cells? Frustrated with inefficient methods and multiple…
Cell Engineering
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Cell Engineering

Cell Engineering

It’s not just sorting and dispensing. Picodroplets are ultra-miniature reaction vessels and can be used…
Cell Line Development
cell line development applications
Cell Line Development

Cell Line Development

Do you wish there was an easier way to ensure only your highest-producing cells are…
Cell Therapy
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Cell Therapy

Cell Therapy

Picodroplets provide a perfect platform for cell therapy development and manufacture. Assess each cell individually…
Our Technology

Built on picodroplet technology

At the heart of our platforms are picodroplets. These are tiny droplets of aqueous fluid in an oil carrier fluid (‘single aqueous’), or an aqueous core surrounded by an oil shell in an aqueous carrier fluid ( ‘double aqueous’).

Each picodroplet is used to encapsulate a cell. This provides an ultra-miniaturized test tube, containing media, reagents and cells, that allows large-scale experiments at the single cell level.

These droplets can then be processed to build complex workflows to find the cells you care about.

Explore our technology
Consumables and Reagents

Consumables and Reagents

Our teams have created an ecosystem of high-quality consumables and reagents optimized for use with Cyto-Mine® to ensure that your workflows are as efficient as possible.

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