- Label free measurement of target molecules
- Retrieve rare cells of interest in real time
- High throughput and low cost
- Customizable workflows
Spectra-Mine®
Spectra-Mine® brings the power of mass spectrometry to picodroplets. It provides a unique, label-free way to automatically identify and select your valuable cells based on mass spectrometry measurements. Our novel approach allows you assess hundreds of thousands of samples each day providing accurate, efficient, low-cost screening - without any fluorescence assays.
Picodroplets + mass spectrometry = results
Mass spectrometry is a powerful measurement technique, but it destroys the sample – not good when you’re looking for a rare cell. Using picodroplets this problem can be solved. Single cells are encapsulated in picodroplets, which retain analytes in each individual droplet. The droplets are incubated to promote cell growth and metabolic processes. Each picodroplet is then split into two daughter picodroplets without loss of the droplet content. One part is injected into the mass spectrometer for measurement using electrospray injection; the other part is kept in a flow channel. The spectrum is analyzed, and the second part selected to be retained if it is a ‘hit’ – all done automatically in real time.
Label-free measurement
Spectra-Mine® extends the power of picodroplets with label-free measurement for selection. Instead of developing a fluorescence assay – which is not always possible – assess your molecules of interest directly, particularly metabolites and other small molecules.
Retrieve your rare cells
Spectra-Mine® solves the problem of destructive measurement. Your cells – all derived from a single clone – are retained in a safe, low-stress picodroplet environment during the spectrum measurement and selected using our established electric-field based picodroplet selection technology.
Customizable workflows
Spectra-Mine® can be configured to match your workflow. Vary the ratio of daughter droplet sizes, include fluorescence or optical measurements, optimize the spectrum analysis algorithms… we work with you to deliver the results you need.
Learn more about Spectra-Mine®
We’re the droplet microfluidic technology company for single cell analysis and our customers are at the center of what we do
Our integrated,
automated platforms
increase efficiency,
delivering value.
Our unmatched
picodroplet technology
is future proof
Our platform is built upon robust evidence from key opinion leaders
Our collaboration with customers is
second to none
Let us show you how our technology adapts to your research.