Pico-Gen™ single aqueous, two inlet filters (40 x 40 µm nozzle)


Pico-Gen™ Picodroplet Generator Biochips are specially designed for generating picodroplets from a single aqueous source.

SKU: C104 Category: Tag:


The Pico-Gen™ Biochips* enable reliable and consistent picodroplet formation with volumes ranging from as small as 60 picolitres up to 1,000 picolitres (hence our use of the term “picodroplets”). Pico-Gen ™ Biochips – 2 filters are designed with one oil inlet port, one aqueous inlet port and one outlet port. They have two integrated in-line filters (one at the oil inlet port and the other at the aqueous inlet port) to minimize blockage of cross-junction nozzles. These Pico-Gen™ Biochips enable the generation of picodroplets 40 – 75 µm in diameter (35 – 220 pL in volume). Simple and safe ‘Plug & Play’ fluidic interfaces facilitate easy connection of the PicoGen™ Biochip to external liquid reservoirs and picodroplet collection devices. All channel surfaces have fluorophilic properties that work perfectly with Sphere Fluidics’ specialist chemical products (e.g. Pico-Surf™, Pico-Break™).

Additional information


Single flow focus geometry.
High picodroplet production rate.
Highly mono-dispersed and reproducible picodroplet sizes ranging from as small as 60 picolitres up to 1,000 picolitres.
Long residence time on chip for easy visualisation.
Simple and safe ‘Plug & Play’ fluidic interface.A comprehensive range of sizes and designs are available.
Excellent transparency for easy picodroplet visualisation.
Fluorophilic channel surface coating for improved performance.Oil inlet in-line filter minimizes flow focus nozzle blockage.
Quick and reliable fluidic connection.



For single cell or multi-cell encapsulation. Compatible with wide range of cell types (bacteria, yeast, CHO cells, Hybridomas, B-cells, T-cells) and molecules.


Pico-Gen™ User Guide


Cyto-Mine® is a powerful fully integrated system that can fast-track antibody discovery and cell line development by delivering selective cell screening, cell isolation and monoclonality assurance.

Research Instruments

Our research instruments can perform single cell screening, protein assays, single cell sorting and dispensing and can be adapted to fit your needs.


We have a wide range of consumables to ensure that you can make the most of our picodroplet technology, including proprietary biochips and specialist chemicals.

Ongoing Development

Ongoing development research and grant funding into CRISPR-Cas9 applications. Interested in working with us? Contact the sales team for more info.