High-Throughput Screening of Antibiotic-Resistant Bacteria with Picodroplets
Summary
This study demonstrates a novel use of microfluidic picodroplet technology to rapidly screen and isolate antibiotic-resistant bacteria. By capturing individual bacterial cells in picodroplets, researchers achieved high-throughput, label-free screening, allowing for the quick identification of antibiotic resistance. This method provides a powerful alternative to traditional screening and offers a potential path forward in combating multidrug-resistant bacteria like Staphylococcus aureus and E. coli. Learn how our technology is accelerating research to address global antibiotic resistance threats.
Research highlights
- Study Title: High-throughput screening of antibiotic-resistant bacteria in picodroplets
- Authors: Liu, X. et al.
- Published In: Lab Chip, Issue 9, 2016 (pp 1636–1643)
- DOI: 10.1098/rsif.2015.0216
Key findings
- Efficient isolation of antibiotic-resistant strains
- Label-free high-throughput screening with picodroplets
- Proof-of-concept demonstrated with E. coli and fusidic acid resistance
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