Accelerating Biologics Discovery and Cell Line Development with Cyto-Mine®Chroma
Discover how picodroplets are transforming workflows for biologics discovery and development in our latest poster.
Our latest poster showcases groundbreaking advancements in biologics discovery and cell line development using Sphere Fluidics’ next-generation Cyto-Mine®.
By integrating picodroplet technology, Cyto-Mine® allows for single-cell analysis, selection, and isolation—radically speeding up the discovery process while ensuring monoclonality.
Whether you’re screening B cell repertoires or advancing cell line development, our second-generation Cyto-Mine® delivers unmatched precision and efficiency.
This cutting-edge technology is helping scientists reduce timelines by 2-3 months, improve cell viability, and increase the chances of finding rare, high-producing clones.
Watch Jessica Hall – Senior Field Application Scientist, discuss the poster presentation at Drug Discovery 2024 in London. Taken by Rizwan Chaudhrey.
Download the poster here:
Download the full poster to explore:
Increased efficiency in gene integration and clone selection
How Cyto-Mine® enables antibody discovery through high-throughput B cell screening
Applications of Cyto-Mine® in antibody discovery and cell line development
Poster Authors: Maryam Ahmadi, Elena Shvets, Frank Gesellchen, Xin Liu, Simona Preiksaite, and Richard Hammond
Contact: Maryam.Ahmadi@spherefluidics.com | info@spherefluidics.com
References:
- Kaplon et. al., Antibodies to watch in 2022, Mabs, 2022.
- Bauer et. al., How can we discover developable antibody-based biotherapeutics?, Front Mol Biosci, 2023.
- Farid et. al., Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D, MAbs, 2020.
The Next Generation: Cyto-Mine® Chroma
Automate. Accelerate. Analyze millions of cells in a single day.
Think Cyto-Mine®, but supercharged, enabling multiplexing and greater assay flexibility to fit your needs. It means that you can examine vastly greater numbers of cells — and isolate the most valuable ones— with unparalleled precision.
