Overcoming challenges in the Cell Line Development process
Advances in cell line engineering and microfluidic technologies provide significant opportunities to reduce timelines in cell line development (CLD). As with any change, optimizing the CLD processes can introduce new challenges and uncertainties.
Some of the key challenges include:
- Selection bias in the cell line
- Unpredictable gene expression
- Issues with automated cloning techniques
- Varying cell growth rates. This article provides an overview of these four challenges and how you can address each scenario. Download to continue reading…
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