Discover High Producing Clones with Monoclonality Assurance in One Day
Streamline Cell Line Development with Cyto-Mine® Technology.
Unmatched Efficiency and Accuracy
In the quest to develop novel biopharmaceuticals, mammalian cell lines must meet stringent criteria, including high productivity, scalability, stability, quality, and monoclonality.
Traditional methods are labor-intensive and slow. Cyto-Mine® revolutionizes this process by encapsulating single cells in picodroplets, conducting antibody secretion assays, and sorting high-producers—all within one day.
Why Choose Cyto-Mine®?
- Single Cell Encapsulation: Using Poisson distribution, cells are encapsulated into picodroplets, optimizing single-cell containment.
- Antibody Secretion Assay: IgG production is measured within hours using animal-origin-free detection reagents, ensuring rapid and accurate assessments.
- Automated Sorting: High-secreting cells are sorted by fluorescence intensity for collection, ensuring only the best candidates proceed.
- Clonality Assurance: Each cell is imaged multiple times to verify clonality before dispensing, providing documented proof.
Results You Can Trust
Our detailed study demonstrates Cyto-Mine®’s capability to handle large cell populations, screening and isolating high-value clones efficiently. The picodroplet-based IgG secretion assay is highly quantitative, covering the typical production range of biopharmaceutical cell types. Key benefits include:
- Simplicity: One-step, automated process.
- Quality: GLP-compliant platform with high isolation accuracy.
- Sterility: End-to-end sterile, disposable, and animal-origin-free.
- Speed: Runs multiple projects in parallel, freeing up valuable time.
- Miniaturization: High-throughput screening with minimal reagent use.
- Traceability: Storable images proving single-cell status ensure monoclonality documentation.
Revolutionize Your Cell Line Development
Cyto-Mine® not only streamlines your workflows but also enhances the quality and speed of your cell line development. By incorporating this innovative technology, you can stay ahead in the competitive field of biopharmaceuticals.
Download the Full Application Note Now
Unlock the potential of Cyto-Mine® in your research by downloading our comprehensive application note. Gain access to detailed methodologies and data that can transform your single-cell analysis approach.
Download now:
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