ESI-Mine™
ESI-Mine™: Picodroplet Mass Spectrometry for High Throughput Single Cell Analysis
In this experiment, femtomole quantities of small molecules were compartmentalised into picolitre volume aqueous droplets called picodroplets and analysed by ESI-Mine™. This video shows the actual mass spectrometry signal recorded during analysis and sorting of the small molecule picodroplet library. Once a ‘hit’ has been detected by mass spectrometry (shown in the mass spectrum data in the lower trace) a yellow flash in the top trace (optical window) indicates the electric pulse which subsequently sorts the complimentary daughter picodroplet.